Arias is listed in the worlds largest and most authoritative dictionary database of abbreviations and acronyms arias what does arias stand for. A search in scielo and pubmed databases using the mesh terms arias stella reaction, endometriosis and adenocarcinoma was done. This code is grouped under diagnosis codes for diseases of the genitourinary system. The condition is a normal physiological process of the body, caused due to hormonal response. Immunohistochemical staining for ki67 and p53 helps. The two patients whose examination exhibited an arias stella reaction were determined to have missed miscarriage, as both had previous ultrasounds that confirmed intrauterine pregnancies. Cove 37 and rhatigan 38 have described cases of endocervical ariasstella reaction that caused confusion with premalignant or malignant conditions. Arias stella reaction, also arias stella phenomenon, is a benign change in the endometrium associated with the presence of chorionic tissue arias stella reaction is due to progesterone primarily. Arias stella reaction benign atypical endometrial changes associated with chorionic tissue may be seen in a completely normal pregnancy and misdiagnosed as. Although these alterations are not infrequent, we have been. This report describes the clinical and pathologic findings in nine nonpregnant women whose endometria demonstrated asr. Arias stella reaction up to 10% of gravid hysterectomy specimens. Arias estella gonadotropina gonadotropina corionica humana.
I found a modified ariasstella reaction in paratubal epithelial cells. It can also refer to changes occurring in the cervix. In an ectopic pregnancy, the uterine endometrium usually responds to the hormonal changes of pregnancy and undergoes focal decidua changes arias stella reaction. Ki67 and p53 immunostaining was significantly less in arias stella reaction than in clear cell carcinoma p 0. In endocervical polyp histologic features similar as in the endometrium. Departments of gynaecology and pathology, university of glasgow. Two patients had a history of oral contraceptive use and 15 were pregnant. The ariasstella reaction is a hormonerelated atypical endometrial change characterized by hypertrophy and vacuolization of glandular epithelial cells, associated with marked nuclear pleomorphism, enlargement, and hyperchromasia. Since its first description more than four decades ago, the atypical endometrial change associated with chorionic tissue effect has been widely confirmed in the literature. Full trisomy 5 in a sample of spontaneous abortion and arias stella reaction. Garcia fu, wojta j, broadley kn, davidson jm, hoove rl.
Studies of hormonal levels obtained from the endocrinologic literature demonstrated declines during early pregnancy at the time of the ovaryplacenta changeover. Hypersrion is prominent and disarray of somewhat hy perchrom atic nuclei give a pseudoneoplastic appearance. Cytologically, it looks like a malignancy and, historically, it was diagnosed as endometrial cancer. The ariasstella phenomenon was first described by javier ariasstella in 1954 as atypical endometrial changes associated with the presence of. That identical cytologic changes may, on occasion, occur outside the endometrium or in nonpregnant women is not as well documented. The authors present a case of arias stella reaction in the fallopian tube and discuss the differential diagnosis of this condition. The same problem was encountered by cariani and guderian 39 and mccormick and menaciwilliams 40 in endocervical polyps with ariasstella reaction. Microscopic examination of the left oviduct seg ments revealed zones of hyperplastic endosalpingeal 14 n. Use of oral contraceptives usually focal, superficial glands. Ariasstella reaction is a hormoneinduced atypical endometrial change that may involve endometrial, extraendometrial, or endometriotic sites.
Endometrio secretor con reaccion arias stella y decidua hemorragica. Both had a history of passing tissue and were diagnosed clinically with incomplete miscarriage. However, the arias stella reaction is exceedingly rare in the fallopian tube, and may be confused with herpetic infection or malignancy. If the ectopic pregnancy miscarries, the uterine decidua may slough off as a cast, but more commonly as fragments mixed with small blood clots. A case report, diagnostic cytopathology, 2005, 32, 2, 94wiley online library. The arias stella reaction asr is a common and universally recognized feature of gestational endometrium. A legal procedure for settling a dispute outside the courts, in which the parties select and agree to abide by the decision of a. Problem the presence of immunosuppressive cells within the endometrium and decidua is crucial for establishing maternal immune tolerance against fetal antigens. Ariasstella reaction, also ariasstella phenomenon, is a benign change in the endometrium associated with the presence of chorionic tissue.
The ariasstella phenomenon and its diagnostic value in ectopic pregnancy. We would like to show you a description here but the site wont allow us. In the case of the young couple described in this paper, arias stella reaction was indicated in both cases of miscarriage. When presenting in extrauterine sites, the differentiation of arias stella changes from other more ominous clear cell lesions may pose. Aviso legal derechos reservados 2012, por red tercer milenio s.
Ectopic pregnancy human chorionic gonadotropin uterus. The arias stella reaction is a hormonerelated atypical endometrial change characterized by hypertrophy and vacuolization of glandular epithelial cells, associated with marked nuclear pleomorphism. Extensive regions of necrosis better microscopic evidence must be sought before making a definitive diagnosis of carcinoma 59. Ariasstella reaction of uterine cervix is a benign tumorlike condition caused due to a change in the cervix. Benign lesions of the cervix the belgian society of. Bartonella bacilliformis stimulates endothelial cells in vitro and is angiogenic in vivo. We report 18 cases of arias stella reaction involving the endocervix with an emphasis on histologic features that can be encountered and result in the misdiagnosis of carcinoma. Ariasstella reaction of uterus is similar to ariasstella reaction of the cervix there are no clearly established risk factors for uterine ariasstella reaction and the cause of tumor formation is unknown. Arias stella reaction like changes in endocervical glandular epithelium in cervical smears during pregnancy and postpartum statesa potential diagnostic pitfall authors j.
Pdf full trisomy 5 in a sample of spontaneous abortion. Acidifique, gota a gota, con acido clorhidrico 6 moll. View enhanced pdf access article on wiley online library html view download pdf for offline viewing. Modified ariasstella reaction in paratubal epithelium. Extensive regions of necrosis in curettings causes degenerating carcinoma septic abortion infarcted polyp degenerated submucosal leiomyoma 58. Full trisomy 5 in a sample of spontaneous abortion and. Originally described in the uterine endometrium, the ariasstella reaction has subsequently been documented outside of the uterine corpus, including fallopian tube, vagina, inclusion cysts of the ovary, paraovarian and paratubal cysts. We decided to evaluate the subpopulations of treg cells and b7h4 macrophages in eutopic. Ariasstella classified the histologic variants into five types. This glandular change is a physiologic response to the presence of chorionic tissue and is probably not directly related to trisomy 5. New york the purpose of this paper is to describe certain endometrial changes which occur in the presence of chorionic tissue and which, it is thought, result from the hormonal activity of this tissue. The ariasstella reaction in early normal pregnancyan.
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